SHARE INDIA provides strategic technical assistance to the Government of India under cooperative agreements supported by the Centers for Disease Control and Prevention (CDC) and the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR).

For over two decades, CDC has partnered with the Ministry of Health and Family Welfare to implement evidence-based, high-impact interventions across HIV and tuberculosis prevention, diagnostics, treatment, retention, and viral load suppression. SHARE INDIA works closely with NACO, NTEP, the Central TB Division, State AIDS Control Societies, and State Health Departments to strengthen laboratory systems, strategic information platforms, service delivery models, and institutional capacity at national, state, and district levels.

Our approach integrates implementation science, digital systems strengthening, workforce capacity building, and policy-aligned technical assistance to support India’s progress toward the UNAIDS 95-95-95 targets and the National Strategic Plan for TB elimination.

LaQSH Plus is a national laboratory systems strengthening initiative implemented under the CDC–PEPFAR cooperative agreement. The project provides strategic technical assistance to NACO under the National AIDS Control Programme (NACP), supporting progress toward the 95–95–95 HIV targets.

With a pan-India footprint — including focused support in North-East states and high-burden geographies — LaQSH Plus strengthens the reliability, reach, and resilience of HIV and STI laboratory systems across the public sector.

1. Viral Load Scale-Up & Optimization

We support operationalization of molecular laboratories for HIV-1 viral load testing through readiness assessments, capacity building, consumable planning, continuous quality improvement (CQI), and lab–clinic interface strengthening to meet national testing demand.

2. Laboratory Quality Management & Accreditation

We provide technical assistance for ISO 15189:2022 transition, QMS strengthening, documentation support, non-conformity closure, and national capacity building workshops to institutionalize quality standards across HIV laboratories.

3. External Quality Assurance & Digital Monitoring

We strengthen national EQAS through proficiency testing, root cause analysis support, and digital reporting platforms such as NACO Prayogshala. KPI dashboards and bulk-upload integrations improve turnaround time, reduce transcription errors, and enhance decision-making.

4. Differentiated Access to Viral Load Testing

We support community-led viral load camps, hub-and-spoke sample collection models, surge strategies in low-coverage districts, and resilient sample transportation systems to ensure uninterrupted services in hard-to-reach and crisis-affected settings.

5. Integrated Diagnostic Models

We demonstrate integrated screening platforms for women living with HIV, including cervical cancer and NCD screening, and support elimination of vertical transmission through strengthened Early Infant Diagnosis (EID) systems.

6. STI Laboratory Network Strengthening

We support etiological testing capacity, antibiotic resistance monitoring, national STI lab assessments, external quality assurance, and strategic consultations to strengthen India’s tiered STI laboratory network.

Viral Load & Coverage

• Supported operationalization and optimization of HIV viral load testing across public sector molecular laboratories nationwide.

• 74% viral load coverage achieved in surge-supported districts, including Mizoram.

• Viral load coverage increased from 9% to 94% in crisis-affected Churachandpur, Manipur through adaptive service models.

Laboratory Quality & Accreditation

• 9 laboratories fully accredited and 17 additional labs transitioned or applied under ISO 15189 standards.

• 396 high-volume HIV testing centres awarded the NACO Certificate of Excellence.

• 5,040+ HIV laboratories onboarded onto the NACO Prayogshala digital EQAS platform.

• 100% of VL and CD4 labs participating in proficiency testing through digital reporting.

Integrated Services & Digital Systems

• 13,849 women living with HIV screened for cervical cancer; 99% of pre-cancer cases successfully treated.

• Bulk-upload VL reporting reduced result upload time from 1–2 hours to under 5 minutes.

• Barcode-based sample tracking rolled out across multiple states, improving traceability and reducing reporting errors.

NISCHIT Plus (HIV) provides targeted technical assistance to strengthen HIV service delivery, advance differentiated care, and enhance treatment quality for people living with HIV (PLHIV) across all districts of Andhra Pradesh, in collaboration with the Andhra Pradesh State AIDS Control Society (APSACS).

The project focuses on improving retention in care, scaling viral load (VL) testing, integrating TB, Hepatitis, and NCD services, and optimizing data systems for real-time program decisions. Through strong collaboration with APSACS, the initiative brings together evidence-based approaches, digital tools, and community-led strategies to deliver person-centered, equitable, and sustainable HIV services.

1. Demonstrate Differentiated Service Delivery Models (DSDM) of Care with Focus on Key and Priority Populations including Children, Adolescents, and Ageing Population

We implement several DSDMs to ensure person-centered HIV care reaches those who need it most — including key populations, children, adolescents. Models include: Family-Centric Care (FCC), which synchronizes visits and ART refills for entire families to strengthen retention and continuity; Fixed-Day Outreach Camps at decentralized and tribal sites, delivering clinical services including ART, VL/CD4 testing, TB and Hepatitis screening, and vaccination to those in hard-to-reach areas; PHC-Based ART Dispensation (NHM Integration), bringing ART refills to Primary Health Centres to reduce travel burden and improve access; and Community ART Refill Groups for Children (CARGs), where adolescents and children self-manage refill schedules with peer support, reducing clinic visits and promoting community-led continuity of care.

2. Advanced Disease Management & Rapid ART Initiation

99% of newly diagnosed PLHIV were initiated on ART. Tracking systems and intensified prophylaxis were established for the 13% presenting with Advanced HIV Disease (AHD). Over 8,109 missed PLHIV were identified and facilitated for baseline VL tests.

3. Re-engagement of Lost to Follow-Up (LFU) Clients

Biannual LFU tracking campaigns using telephonic outreach, treatment literacy messaging, and real-time dashboards resulted in 94% of LFUs contacted and 16,610 clients successfully re-engaged in care as of April 2025.

4. U=U Clinics for Unsuppressed PLHIV

Peer-led U=U Clinics provide focused adherence support for PLHIV with unsuppressed viral loads through monthly counselling, treatment literacy, and community champion sessions with dedicated clinic days for consistent follow-up.

5. NCD Integration into Routine HIV Care

Hypertension and diabetes screening, diagnosis, and treatment have been integrated into routine ART services. Self-screening BP monitors are installed in waiting areas at high-load ART Centres. Cervical cancer screening is also provided for women living with HIV.

6. Viral Load Scale-Up & Suppression

A multi-pronged VL strategy uses centre-wise line lists, outreach to sub-populations, decentralized sample collection, and fishbone-method root cause analysis to prioritize never-tested and unsuppressed PLHIV.

7. TB Preventive Therapy (1HP)

Following the revised NACO Operational Manual (July 2024), 3,391 PLHIV were initiated on the 1HP regimen within six weeks across select Andhra Pradesh districts, with daily reporting enabling real-time stock and uptake tracking.

8. Integrated Hepatitis B & C Services

Hepatitis B vaccination was rolled out across 54 ART centres. Between February 2023 and January 2024, 89% of Hepatitis B-negative PLHIV received their first vaccine dose. Over 100,000 doses were delivered within 90 days without stockouts.

9. Data Intelligence & Digital Tools

Fuzzy Lookup tools corrected 2,647 duplicate records. Looker Studio dashboards support real-time LFU monitoring. Field insights were shared with NACO, contributing to national enhancement of the SOCH platform.

Differentiated Service Delivery Models for Improved Access to Care and Retention

• Family-Centric Care (FCC): Synchronizes ART refill visits and coordinates holistic care for entire families, improving retention and ensuring uninterrupted treatment for all family members living with HIV.

• Decentralised ART Dispensation: ART refills delivered through Primary Health Centres (PHCs), bringing services closer to clients and reducing the burden of travel to ART Centres.

• Fixed-Day Outreach Camps: Organized at peripheral and tribal sites to reach PLHIV in remote areas, delivering clinical care including ART dispensation, VL/CD4 testing, TB and Hepatitis screening, and vaccination on designated days.

Viral Load & Suppression

• 3,391 PLHIV initiated on 1HP TB preventive therapy within six weeks of rollout.

Comorbidity & Integrated Services

• 55% of PLHIV screened for hypertension; 2,037 initiated on treatment.

• 48% of PLHIV screened for diabetes; 1,627 initiated on treatment.

• 89% of Hepatitis B-negative PLHIV received the first vaccine dose; 100,000+ doses delivered in 90 days.

• 6,809 PLHIV reached through fixed-day outreach camps including key populations and children.

Data & Digital Systems

•  duplicate records corrected via Fuzzy 

• Real-time dashboards operationalized for LFU monitoring; advanced tools for improving program reporting accuracy, insights contributed to national SOCH platform design.

NISCHIT Plus (TB) provides technical assistance to the National TB Elimination Program (NTEP) under the Ministry of Health and Family Welfare, Government of India, in collaboration with the Central TB Division and State TB Offices. This initiative strengthens implementation of the National Strategic Plan across its four pillars — Prevent, Detect, Treat, and Build — advancing India’s TB elimination goals.

With a pan-India presence, the project supports healthcare institutions, high-burden urban settlements, pediatric populations, household contacts of TB patients, healthcare workers, and congregate settings across multiple states and Union Territories.

1. Institutionalizing Infection Prevention & Control (IPC) Systems

We strengthen IPC systems across healthcare facilities through structured assessments, building the capacity of hospital infection control committees, digital compliance dashboards, and implementation of administrative and environmental control measures.

2. Expanding Access to TB Infection Testing & Preventive Therapy

We support systematic household contact screening, IGRA-based testing, initiation and follow-up of TB Preventive Therapy, and data-driven approaches to identify and reach missed populations.

3. Protecting Healthcare Workers & High-Risk Populations

We implement structured TB infection screening for healthcare workers, strengthen occupational health safeguards, promote adherence to infection control practices, and support preventive therapy initiation where indicated.

4. Enhancing Pediatric TB Detection Pathways

We engage Anganwadi centres and schools to improve early symptom identification, strengthen referral linkages to diagnostic services, and facilitate timely linkage to treatment for children with TB.

5. Strengthening District-Level Data Validation & Analytics

We build the capacity of district and sub-district program staff in data validation and analysis, support real-time monitoring systems, and enable evidence-based district action planning.

6. Translating Evidence into Program Improvements

We document implementation learnings, generate operational evidence, and integrate research findings into routine program planning and policy refinement.

Infection Prevention & Control

• 4,300+ healthcare personnel trained in TB-IPC practices.

• 222 healthcare facilities completed baseline and quarterly IPC assessments using a standardized 61-indicator tool.

• State-level dashboards operationalized for real-time IPC compliance monitoring.

Healthcare Worker Protection (PrTHAM — Sevagram)

• 2,071 healthcare workers enrolled for LTBI testing using IGRA and Cy-TB.

• 223 initiated on TB Preventive Therapy with an 85% completion rate.

• 1,370 personnel trained in structured IPC sessions.

Household Contact & LTBI Interventions (HaALT — Nagpur)

• 1,038 household contacts tested; 44% identified as LTBI positive.

• 283 completed TB Preventive Therapy; 1,305 contacts followed at six-month intervals.

• 23 active TB cases identified and linked to treatment.

Data-Driven TB Prevention (Delhi, Sikkim, Karnataka)

• 1,304 close contacts reached; 439 initiated on TB Preventive Therapy.

• Hotspot mapping and AI-assisted chest X-rays deployed for enhanced early detection.

Pediatric TB Strengthening

• 569 Anganwadi centres and 249 schools reached in Mumbai; additional outreach conducted in Delhi.

• 140 individuals referred; 6 diagnosed and linked to treatment.

Under the BOLSTER initiative, SHARE INDIA works with the Government of India and the Centers for Disease Control and Prevention (CDC) to strengthen India’s capacity to prevent, detect, and respond to infectious disease threats.

The project advances a One Health approach, integrating human, animal, and environmental health systems to build resilient surveillance, laboratory, and outbreak response mechanisms.